LI Yuhua, ZHAO Jinhua. Systemic Nursing Experience of a Patient with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)[DB/OL].Clinical Archives of Integrative Medicine, 2026.
DOI:
LI Yuhua, ZHAO Jinhua. Systemic Nursing Experience of a Patient with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)[DB/OL].Clinical Archives of Integrative Medicine, 2026. DOI: 10.12209/CAIM202510100001.
Systemic Nursing Experience of a Patient with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)
This paper summarizes the systematic nursing experience of a patient with Toxic Epidermal Necrolysis (TEN) involving >90% total body surface area (TBSA) epidermal detachment. Based on multidisciplinary team (MDT) collaboration, prospective and systematic nursing was implemented for a 27-year-old critically ill female patient, including phased individualized wound management, multimodal pain management, strict infection control, personalized nutritional support, and full-course psychological support. After 20 days of systematic intervention, the patient achieved 30% TBSA epidermal regeneration, normalized infection indicators, significantly improved pain and nutritional status, and was successfully transferred to the burn department for further treatment. Practice has shown that prospective and systematic nursing for critically ill TEN patients is crucial to improving treatment success rates and prognosis.
关键词
Keywords
references
Smith A , Jones B . Global incidence of Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review [J]. Journal of Dermatological Science , 2022 , 105 ( 2 ): 45 - 50 .
Brown C , et al . Mortality predictors in toxic epidermal necrolysis: a multicenter cohort study [J]. Burns , 2021 , 47 ( 5 ): 1120 - 1125 .
Lee D , Wang E . Nursing challenges in severe Stevens-Johnson syndrome: a case analysis [J]. Clinical Nursing Research , 2023 , 32 ( 3 ): 210 - 215 .
DUONG T A , VALEYRIE-ALLANORE L , WOLKENSTEIN P , et al . Severe cutaneous adverse reactions to drugs [J]. Lancet , 2017 , 390 ( 10106 ): 1996 - 2011 .
NOE M H , MICHELETTI R G . Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis [J]. Clin Dermatol , 2020 , 38 ( 6 ): 607 - 612 .
ZHANG W L , PAN J B , LI H . Efficacy of enteral nutritional support in patients with Stevens-Johnson syndrome(SJS)/toxic epidermal necrolysis(TEN) [J]. Parenter Enter Nutr , 2025 , 32 ( 3 ): 151 - 154, 164 . (in Chinese)
HU X , LIANG G P , WANG H , et al . Stevens-Johnson syndrome/toxic epidermal necrolysis: a retrospective study of 104 cases [J]. Chin J Dermatol , 2024 , 57 ( 12 ): 1114 - 1120 . (in Chinese)
International Society of Burn Injuries . Guidelines for the management of Stevens-Johnson syndrome and toxic epidermal necrolysis [J]. Burns , 2022 , 48 ( 4 ): 789 - 798 .
Micheletti RG , Rosenbach M , Kaffenberger BH , et al . Medical care of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States [J]. Journal of the American Academy of Dermatology , 2022 , 87 ( 4 ): 845 - 853 .
Yang CS , Lee YJ , Chu CY , et al . Expert consensus on the management of Stevens-Johnson syndrome and toxic epidermal necrolysis in Taiwan [J]. Journal of the Formosan Medical Association , 2023 , 122 ( 5 ): 422 - 432 .
Tombs M , Oulee A , Muthumakumar N , et al . Multidisciplinary care in toxic epidermal necrolysis: a systematic review and meta-analysis [J]. Burns , 2024 , 50 ( 1 ): 23 - 34 .
Dodiuk-Gad RP , Chung WH , Valeyrie-Allanore L , et al . SCORTEN and ASCORTEN: A review of scoring systems for Stevens-Johnson syndrome and toxic epidermal necrolysis [J]. Journal of the American Academy of Dermatology , 2023 , 88 ( 2 ): 361 - 367 .
MORSE J M , BLACK C , OBERLE K , et al . A prospective study to identify the fall-prone patient [J]. Soc Sci Med , 1989 , 28 ( 1 ): 81 - 86 .
BERGSTROM N , BRADEN B J , LAGUZZA A , et al . The braden scale for predicting pressure sore risk [J]. Nurs Res , 1987 , 36 ( 4 ): 205 - 210 .
MAHONEY F I , BARTHEL D W . Functional evaluation: the barthel index [J]. Md State Med J , 1965 , 14 : 61 - 65 .
WILLIAMSON A , HOGGART B . Pain: a review of three commonly used pain rating scales [J]. J Clin Nurs , 2005 , 14 ( 7 ): 798 - 804 .
KONDRUP J , RASMUSSEN H H , HAMBERG O , et al . Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials [J]. Clin Nutr , 2003 , 22 ( 3 ): 321 - 336 .
GORSKI L A , HADAWAY L , HAGLE M E , et al . Infusion therapy standards of practice, 8th edition [J]. J Infus Nurs , 2021 , 44 ( 1S ): S1 - S224 .
Kwiecien K , Kopeć U , Brzezinski M , et al . Modern wound care in the treatment of toxic epidermal necrolysis: a systematic review and meta-analysis [J]. Advances in Dermatology and Allergology , 2024 , 41 ( 1 ): 45 - 55 .
GREGORY D G . The ophthalmologic management of acute stevens-Johnson syndrome [J]. Ocul Surf , 2008 , 6 ( 2 ): 87 - 95 .
Mervic M , Stubjar D , Stubjar N , et al . Pain management in patients with toxic epidermal necrolysis: A narrative review [J]. Burns , 2023 , 49 ( 7 ): 1491 - 1499 .
Barrow MJ , Kuo YL , Williams G , et al . The pivotal role of nursing in the multidisciplinary management of toxic epidermal necrolysis: A case series and literature review [J]. Burns , 2024 , 50 ( 2 ): 456 - 465 .
Gupta MA , Goddard A , Grunberg P , et al . Virtual reality for procedural pain and anxiety in patients with Stevens-Johnson syndrome/toxic epidermal necrolysis: a pilot study [J]. Journal of Burn Care & Research , 2023 , 44 ( 3 ): 678 - 685 .
Case Report on TCM Nursing for a Patient with Thyroid Nodules of Qi Stagnation and Phlegm Coagulation Type
Nursing Experience of a Patient with Severe Intestinal Obstruction after Radical Cystectomy with Ileal Conduit for Bladder Cancer
Case Analysis of Integrated Traditional Chinese and Western Medicine Nursing for a Patient with Acute Cerebral Infarction (Stroke Disease) Caused by Phlegm-Heat Stasis Obstruction
Nursing Experience of a Case of Stage 3 Pressure Injury in a Disabled Elderly Patient
Nursing Report on the Treatment of One Case of Occipital Neuralgia with Qi Deficiency and Blood Stasis Using Fire Dragon Cupping Combined with Moxibustion
Related Author
KANG Jie
KANG Qing
CUI Xin
DU Juan
FAN Jiao
TIAN Runxi
FENG Yingying
JIN Yaping
Related Institution
Department of Nursing, Dongzhimen Hospital, Beijing University of Chinese Medicine
Department of Outpatient Surgery, Dongzhimen Hospital, Beijing University of Chinese Medicine
Department of Radiology, Dongzhimen Hospital, Beijing University of Chinese Medicine
Department of Outpatient Ultrasound, Dongzhimen Hospital, Beijing University of Chinese Medicine
Ophthalmology Clinic, Huashi Community Health Service Center, Dongcheng District