YANG Zhijie, YANG Man, BAO Wenxian. Nursing Report on Quadruple Therapy of External Traditional Chinese Medicine for a Patient with Sjögren’s Syndrome-Related Dry Eye[DB/OL].Clinical Archives of Integrative Medicine, 2026.
DOI:
YANG Zhijie, YANG Man, BAO Wenxian. Nursing Report on Quadruple Therapy of External Traditional Chinese Medicine for a Patient with Sjögren’s Syndrome-Related Dry Eye[DB/OL].Clinical Archives of Integrative Medicine, 2026. DOI: 10.12209/CAIM202602130001.
Nursing Report on Quadruple Therapy of External Traditional Chinese Medicine for a Patient with Sjögren’s Syndrome-Related Dry Eye
This article summarizes the integrated traditional Chinese and Western medicine nursing experience for a patient with Sjögren’s syndrome-related dry eye. Given the short-lasting efficacy and recurrent symptoms of conventional drug therapy, the nursing team implemented quadruple therapy of external Traditional Chinese Medicine (TCM)—including herbal eye fumigation, herbal eye patches, holographic scraping around the eyes, and finger acupressure—alongside syndrome-differentiated nursing care, while maintaining baseline treatment with hydroxychloroquine sulfate, total glucosides of peony, and oral Chinese herbal medicine. Complementary interventions included Five-Element music therapy for emotional regulation and syndrome-adapted dietary guidance. After 7 days of systematic intervention, the patient’s symptoms of ocular dryness and foreign body sensation significantly improved. The Schirmer’s test (SIT) results increased from 4 mm to 13 mm in the left eye and from 2 mm to 8 mm in the right eye. The Ocular Surface Disease Index (OSDI) score improved from severe to mild, with concurrent alleviation of anxiety and sleep quality. The findings suggest that this quadruple therapy effectively enhances periocular microcirculation and systemic symptoms in dry eye patients, with advantages of simplicity and safety, meriting clinical promotion.
ZHANG X , LI X Y , ZHANG X W , et al . Research progress in treatment of Sj? gren′s syndrome by traditional Chinese medicine [J]. China J Chin Mater Med , 2023 , 48 ( 12 ): 3235 - 3245 . (in Chinese)
XU H D , JIANG Q , CHENG Z Y , et al . Research progress on treatment of primary Sj? gren’s syndrome from the deficiency of both qi and Yin [J]. China J Tradit Chin Med Pharm , 2023 , 38 ( 6 ): 2720 - 2723 . (in Chinese)
ZHOU X Y , JIANG Q , TANG X P , et al . Expert Consensus on TCM Syndromes of Sjögren's Syndrome [J]. J Beijing Univ Tradit Chin Med , 2023 , 46 ( 3 ): 310 - 314 . (in Chinese)
FENG L , XU Y Y , LI M Y . Efficacy of hydroxychloroquine sulfate on sjogren’s syndrome and its effects on levels of serum IL-17 ESR CRP and IgG [J]. Hebei Med , 2021 , 27 ( 2 ): 334 - 339 . (in Chinese)
MARINHO A , DELGADO ALVES J , FORTUNA J , et al . Biological therapy in systemic lupus erythematosus, antiphospholipid syndrome, and Sjögren’s syndrome: evidence- and practice-based guidance [J]. Front Immunol , 2023 , 14 : 1117699 .
LIANG C L , JIANG H L , FENG W X , et al . Total glucosides of paeony ameliorate pristane-induced lupus nephritis by inducing PD-1 ligands+ macrophages via activating IL-4/STAT6/PD-L2 signaling [J]. Front Immunol , 2021 , 12 : 683249 .
DU T T , JIN L Z , LI L . The effect of Runfei Huayu decoction combined with hydroxychloroquine sulfate for sjögren’s syndrome of qi deficiency and blood stasis type [J]. Tradit Chin Med Rehabil , 2025 , 2 ( 12 ): 32 - 36 . (in Chinese)
WU J L , AN Z P , WANG S M , et al . Study on reliability and validity of ADL Scale in patients with stroke [J]. Chin J Contemp Neurol Neurosurg , 2009 , 9 ( 5 ): 464 - 468 . (in Chinese)
XU C J , YAO L , SHI Y H , et al . Application of risk management for preventing inpatients' fall/fall from bed [J]. Chin Nurs Manag , 2013 , 13 ( 5 ): 66 - 69 . (in Chinese)
SCHIFFMAN R M . Reliability and validity of the ocular surface disease index [J]. Arch Ophthalmol , 2000 , 118 ( 5 ): 615 .
LIU X C , TANG M Q , HU L , et al . Reliability and validity of the Pittsburgh sleep quality index [J]. Chin J Psychiatry , 1996 , 29 ( 2 ): 103 - 107 . (in Chinese)
DUAN Q Q , SHENG L . Differential validity of SAS and SDS among psychiatric non-psychotic outpatients and their partners [J]. Chin Ment Health J , 2012 , 26 ( 9 ): 676 - 679 . (in Chinese)
WANG S H , LI J X , ZI H . Clinical Research Progress on the Treatment of Dry Eye Syndrome with Traditional Chinese Medicine Fumigation [J]. Hunan J Tradit Chin Med , 2025 , 41 ( 3 ): 186 - 189 . (in Chinese)
LIU X H , ZOU H D , LI J , et al . Effects of Fuming and steaming and lacrimal plug treatment on vision-related quality of life of severe dry eye [J]. China J Chin Ophthalmol , 2019 , 29 ( 3 ): 202 - 205 . (in Chinese)
WANG Y , HE D , CHEN Y J . Research progress of traditional Chinese medicine characteristic therapy for dry eye [J]. Chin Clin Nurs , 2024 , 16 ( 1 ): 52 - 55 . (in Chinese)
DAI M L , LUO X X , WANG J P , et al . Clinical research progress of TCM characteristic therapy in treating xerophthalmia [J]. China’s Naturopathy , 2025 , 33 ( 21 ): 110 - 114 . (in Chinese)
YANG L , YANG Z G , YU H , et al . Acupuncture therapy is more effective than artificial tears for dry eye syndrome: evidence based on a meta-analysis [J]. Evid Based Complementary Altern Med , 2015 , 2015 : 143858 .
HUANG Q J , SUN Y C , HUANG L H . The impact of music therapy combined with systematic psychological defense on the quality of life of patients with Sjögren's syndrome [J]. China Health Stand Manag , 2024 , 15 ( 22 ): 176 - 179, 185 . (in Chinese)
CHENG F , ZHAO F T , SHEN X M , et al . Multidisciplinary Diagnosis and Treatment Expert Consensus for Primary Sjögren's Syndrome (2024 Edition) [J]. J Intern Med Concepts Pract , 2024 , 19 ( 6 ): 357 - 362 . (in Chinese)
ZHANG Y , YANG J Y , ZHANG L N , et al . Tongue Manifestations and Syndrome Characteristics of Patients with Primary Sjögren's Syndrome at Different Disease Stages [J]. Chin J Exp Tradit Med Formulae , 2023 , 29 ( 8 ): 52 - 58 . (in Chinese)
Integrated Traditional Chinese and Western Nursing Report on the Treatment of a Case of Meige Syndrome with Suboptimal Post-DBS Outcomes Using TCM Appropriate Techniques
Nursing Report on Ginger-Fluff Wax Therapy Combined with Meridian-Sinew Acupuncture for a Post-Stroke Patient with Upper Limb Spastic Paralysis
Nursing Report of a Maintenance Hemodialysis Patient with Star Fruit Intoxication-Induced Metabolic Encephalopathy Managed Under the Comprehensive Chain Care "1+1" Model
Nursing care of a patient with limb dysfunction after clavicle fracture using mirror therapy combined with traditional Chinese medicine nursing to improve clinical symptoms
A nursing report on the treatment of type II knee synovitis with cold dampness obstruction using Liu's fire ironing technique
Related Author
WANG Yingying
LIU Xin
DENG Jianhua
LI Mengya
HU Fangfang
LI Yuxin
ZHANG Ying
WEN Zonglin
Related Institution
Department of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Department of Nephrology, Dongfang Hospital Beijing University of Chinese Medicine
Department of massage, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Preventive Medicine Center, Huangyan District Traditional Chinese Medicine Hospital
Department of Administrative, Huangyan District Traditional Chinese Medicine Hospital