Nursing Experience of Auricular Active-Dredging Tuina Combined with Ear Apex Bloodletting in Managing Cetuximab-Induced Skin Rash in a Patient with Advanced Sigmoid Colon Cancer
|更新时间:2026-09-09
|
Nursing Experience of Auricular Active-Dredging Tuina Combined with Ear Apex Bloodletting in Managing Cetuximab-Induced Skin Rash in a Patient with Advanced Sigmoid Colon Cancer
ZHAO Dan, YANG Mo, LI Xue, et al. Nursing Experience of Auricular Active-Dredging Tuina Combined with Ear Apex Bloodletting in Managing Cetuximab-Induced Skin Rash in a Patient with Advanced Sigmoid Colon Cancer[DB/OL].Clinical Archives of Integrative Medicine, 2026.
DOI:
ZHAO Dan, YANG Mo, LI Xue, et al. Nursing Experience of Auricular Active-Dredging Tuina Combined with Ear Apex Bloodletting in Managing Cetuximab-Induced Skin Rash in a Patient with Advanced Sigmoid Colon Cancer[DB/OL].Clinical Archives of Integrative Medicine, 2026.DOI: 10.12209/CAIM202604270001.
Nursing Experience of Auricular Active-Dredging Tuina Combined with Ear Apex Bloodletting in Managing Cetuximab-Induced Skin Rash in a Patient with Advanced Sigmoid Colon Cancer
This article summarizes the nursing experience of traditional Chinese medicine (TCM) interventions, specifically auricular active-dredging Tuina combined with ear apex bloodletting, applied to a patient with advanced sigmoid colon cancer who developed CTCAE Grade 2 cutaneous adverse reactions following cetuximab combined with chemotherapy. Based on TCM pattern differentiation, the patient was diagnosed with spleen deficiency with dampness-heat, dampness-heat accumulation in the skin, and phlegm-toxin stasis obstruction. The nursing protocol incorporated auricular active-dredging Tuina and ear apex bloodletting, in conjunction with syndrome-differentiated dietary therapy and Gong-tone music therapy for emotional regulation, aiming to clear heat and resolve toxins, eliminate dampness and unblock collaterals, as well as harmonize qi and blood. Following the intervention, the patient's rash-related pruritus was significantly alleviated, with notable improvements in sleep quality and anxiety status. This approach is safe, convenient, and demonstrates preliminary efficacy, thereby offering a valuable reference for clinical practice.
关键词
Keywords
references
Saoudi González N , Ros J , Baraibar I , et al . Cetuximab as a key partner in personalized targeted therapy for metastatic colorectal cancer [J]. Cancers , 2024 , 16 ( 2 ): 412 .
Wang G , Xiang L H , Yuan Y , et al . Expert consensus on management of skin toxicities induced by anti-EGFR monoclonal antibody [J]. J Pract Oncol , 2021 , 36 ( 3 ): 195 - 201 . (in Chinese)
Iimura Y , Iihara H , Saito Y , et al . Epidermal growth factor receptor inhibitor-related skin toxicities: a review of management and possible preventive and therapeutic approaches for Asian patients by the Japanese Pharmacist-led Oncodermatology Study Team [J]. Int J Clin Oncol , 2025 , 30 ( 11 ): 2192 - 2207 .
Cortez S , Martins R , Silva M . Limitations of conventional corticosteroid and oral antibiotic therapy for cetuximab-induced acneiform rash in metastatic colorectal carcinoma [J]. J Eur Acad Dermatol Venereol , 2025 , 39 ( 8 ): 1871 - 1878 .
Dong T T , Gao H R , Zhang W L . Clinical case of ephedra, forsythia and Chixiaodou decoction combined with Chushi Zhiyang decoction in treating eczema with spleen deficiency and dampness accumulation [J]. China’s Naturopathy , 2024 , 32 ( 4 ): 103 - 105 . (in Chinese)
Silva R , Ferreira L , Oliveira T . Karnofsky performance status as baseline prognostic indicator in metastatic colorectal cancer receiving anti-EGFR targeted therapy [J]. J Clin Lab Anal , 2025 , 39 ( 7 ): e24963 .
Cai L Q , Cheng X Z , Zhang K J , et al . Comparison of commonly used fall risk assessment tools in predicting fall risk: a prospective observational study in older adult inpatients over 80 Years of age [J]. West J Nurs Res , 2025 , 47 ( 5 ): 376 - 383 .
Jiang Q X , Liu G Z , Zhu Y L , et al . Study on the applicability and optimal cut-off of Braden Scale in the diagnosis of pressure injury in the elderly based on multicenter study data [J]. Chin J Nurs , 2023 , 58 ( 4 ): 440 - 445 . (in Chinese)
Xu Q C , Yang H Z , Shi L , et al . The predictive value of preoperative NRS2002 score for survival in patients with colorectal cancer: an analysis based on the DACCA database [J]. Chin J Bases Clin Gen Surg , 2024 , 31 ( 6 ): 676 - 681 . (in Chinese)
Wang Y , Wang G , Li H Y , et al . Impact of short-term application of methylprednisolone combined with multimodal analge-sia on intestinal function recovery after colorectal cancer surgery [J]. J Colorectal Anal Surg , 2025 , 31 ( 3 ): 237 - 244 . (in Chinese)
Chinese Society of Dermatology and Venereology , Chinese Medical Doctor Association Dermatology Branch , Chinese Society of Geriatric Medicine Dermatology Branch . Chinese expert consensus on diagnosis and treatment of immune checkpoint inhibitor-related skin adverse reactions (2024 edition) [J]. Natl Med J China , 2024 , 104 ( 20 ): 1790 - 1803 . (in Chinese)
Zheng J Y , Yu B Q , Chen X X , et al . Characteristics of pruritus in adult patients with psoriasis vulgaris and its effect on quality of life [J]. Chin J Dermatol , 2022 , 55 ( 9 ): 790 - 794 . (in Chinese)
Zhang B Q , Zhao X M , He Y , et al . Cognitive behavioral therapy for chronic insomnia disorder: analysis of relevant clinical characteristics and neuropsychological factors [J]. J Brain Nerv Dis , 2026 , 34 ( 5 ): 272 - 276 . (in Chinese)
Donker T , van Straten A , Marks I , et al . Quick and easy self-rating of Generalized Anxiety Disorder: validity of the Dutch web-based GAD-7, GAD-2 and GAD-SI [J]. Psychiatry Res , 2011 , 188 ( 1 ): 58 - 64 .
Martin A , Rief W , Klaiberg A , et al . Validity of the brief patient health questionnaire mood scale (PHQ-9) in the general population [J]. Gen Hosp Psychiatry , 2006 , 28 ( 1 ): 71 - 77 .
Yin H L . Auricular acupoint sticking-pressing and ear-apex bloodletting therapy for a young adult patient with acne of dampness-heat of spleen and stomach type and related nursing management [J]. Chin J Integr Nurs , 2022 ( 6 ): 111 - 114 . (in Chinese)
Cui S M , Zhang H R , Zhang X H , et al . Experience in the syndrome differentiation and treatment of skin adverse reactions related to tumor targeted therapy [J]. Beijing J Tradit Chin Med , 2024 , 43 ( 9 ): 1071 - 1074 . (in Chinese)
Zhuang B Y , Huang J L , Nong Q L . Traditional Chinese Medicine characteristic nursing of a patient with facial rash caused by cetuximab [J]. Chin J Integr Nurs , 2023 ( 11 ): 7 - 10 . (in Chinese)
Nursing Experience of One Case of Postoperative Sleep Disorder Following Mixed Hemorrhoids Surgery Improved by "Sunshine Illumination Method" Combined with Fire Dragon Cupping Therapy
Nursing Experience of Bian-Stone Therapy Combined with Local Infrared Irradiation for Postoperative Pain Management in a Patient with Mixed Hemorrhoids
Case Practice of Acupoint Massage Combined with Traditional Chinese Medicine External Application in Pain Management for a Patient with Lumbar Disc Herniation
Nursing Experience of Applying Balanced Cupping Therapy Based on the "Midnight-Noon Ebb-Flow Timing Theory" for One Patient with Spleen-Deficiency and Dampness-Stagnation Abdominal Obesity
Nursing Report of Bamboo Cupping Combined with Acupoint Bloodletting for One Patient with Postherpetic Neuralgia
Related Author
WANG Changyue
CUI Shujie
PEI Xiaolu
LI Yudong
YUE Lina
WANG Changyue
ZHANG Tingting
TIAN Cuifang
Related Institution
The Second General Surgical Ward, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Department of Nursing, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Department of Anorectal Surgery, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Comprehensive Surgical Ward II, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Department of Proctology, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University